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BST DNA Polymerase Large Fragment 8U/µl

8,000.00

It is an in silico designed homologue of Bacillus

stearothermophilus DNA Polymerase I, Large Fragment (Bstl DNA Polymerase, Large Fragment) with a reversibly-bound aptamer, which inhibits polymerase activity at temperatures below 50°C. The aptamer rapidly releases the Bstl DNA Polymerase above 50°C and therefore no special activation step is needed to activate the polymerase.

 

Description

It is an in silico designed homologue of Bacillus

stearothermophilus DNA Polymerase I, Large Fragment (Bstl DNA Polymerase, Large Fragment) with a reversibly-bound aptamer, which inhibits polymerase activity at temperatures below 50°C. The aptamer rapidly releases the Bstl DNA Polymerase above 50°C and therefore no special activation step is needed to activate the polymerase.

Bstl DNA Polymerase contains 5′-3′ DNA polymerase activity and strong strand displacement activity but lacks 5′-3′ exonuclease activity. Bst DNA Polymerase displays improved amplification speed, yield, salt tolerance, and thermo stability compared to wild-type Bstl DNA Polymerase, Large Fragment.